Brain Mets
CCTG CE.7 - A Phase III Trial of Stereotactic Radiosurgery Compared with Whole Brain Radiotherapy (WBRT) for 5-15 Brain Metastases(DCP)
NCT03550391
NRG-BN012 - A Randomized Phase III Trial of Pre-Operative Compared to Post-Operative Stereotactic Radiosurgery in Patients with Resectable Brain Metastases
NCT05438212
Breast
Triple Negative
Node + / low risk/ HER2-
CCTG MA.39 - Tailor RT: Rand Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer(DCP)
HER2+
NRG-BR008 - A Phase III Randomized Trial of Radiotherapy Optimization for Low-Risk HER2-Positive Breast Cancer (HERO*) *Her2 Radiation Optimization (HERO)(DCP)
NCT05705401
S2010 - A Randomized Phase III Trial Comparing Active Symptom Monitoring Plus Patient Education Versus Patient Education Alone To Improve Persistence With Endocrine Therapy In Young Women With Stage I-III Breast Cancer (ASPEN)
HER2-
NRG-BR007 - A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER2-Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA) (DCP)
NCT04852887
NRG-BR009 - A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients with pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score(DCP)
NCT05879926
Cancer Control
GI
Colon
A022101 - A Pragmatic Randomized Phase III Trial Evaluating Total Ablative Therapy for Patients with Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur) (DCP)
NCT05673148
NRG-GI008 - Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-NORTH AMERICA)
NCT05174169
Anal
Esophageal / GE-Junction/ Gastric
Small Bowel
Pancreatic
Gallbladder
Rectal
EA2201 - Ph II Study of Neoadjuvant Nivolumab Plus Ipilimumab & Short-Course Radiation in MSI-H / dMMR Locally Advanced Rectal Adenocarcinoma (suspended)
Cancer Control
IM2021-064 - Evaluating the Utility of Compression Therapy on Decreasing Chemotherapy-Induced Peripheral Neuropathy: A Pilot Clinical Study
GU
Bladder
Cancer Control
Prostate
Head and Neck
Oropharyngeal
Nasopharyngeal
Heme
Amyloidosis
MM
S1803 - Ph III Study of Daratumumab/rHuPH20 + Lenalidomide or Lenalidomide as Post-Autologous Stem Cell Transplant Maintenance Therapy in Pts w/ MM Using Minimal Residual Disease to Direct Therapy Duration (DRAMMATIC Study) (DCP)
NCT04071457
S2209 - A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a Subset of "Intermediate Fit" Comparing Upfront Three-Drug Induction Regimens Followed by Double or Single-Agent Maintenance
NCT05561387